Title

Exome Sequencing of Pleuropulmonary Blastoma Reveals Frequent Biallelic Loss of TP53 and Two Hits in DICER1 Resulting in Retention of 5p-Derived miRNA Hairpin Loop Sequences.

Document Type

Journal Article

Publication Date

11-6-2014

Journal

Oncogene

Volume

33

Issue

45

DOI

10.1038/onc.2014.150

Keywords

Base Sequence; Chromosomes, Human, Pair 5; DEAD-box RNA Helicases; DNA Copy Number Variations; Exome; Female; GTP Phosphohydrolases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lung Neoplasms; Male; Membrane Proteins; MicroRNAs; Mutation; Nucleic Acid Conformation; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins B-raf; Pulmonary Blastoma; Reverse Transcriptase Polymerase Chain Reaction; Ribonuclease III; Sequence Analysis, DNA; Tumor Suppressor Protein p53

Peer Reviewed

1

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