Medication Adherence and its Implications for Clinical Research: An Example from Low Income, Urban Young Adults Living with HIV/AIDS
The 27th Annual Conference of the Society of Clinical Research Associates
Medication Adherence; HIV; AIDS; Clinical Research
Consistent medication adherence by study participants is essential for producing valid and reliable safety and efficacy data in clinical trials. Adherence to investigational medications can be a challenge, particularly for study participants who have complex medication regimens, a stigmatized illness such as HIV/AIDS or a mental health disorder, and risk factors for poor adherence such as young or old age, poor health status, cognitive issues, low health literacy, and low socioeconomic status. A deep understanding of the study population’s beliefs, attitudes, motivations, and prior experiences regarding medication adherence can assist clinical research professionals with predicting medication adherence potential during the recruitment phase along with supporting medication adherence during the study conduct phase. I will present excerpts from in-depth interviews with 16 low income, urban young adults living with HIV/AIDS about their beliefs, attitudes, motivations, and prior experiences about medication adherence. I will discuss how this information can be used by clinical research professionals who conduct clinical trials with this population to predict and support medication adherence. I will also discuss how collecting deep, rich qualitative data about the study population can assist the clinical research team with predicting and supporting medication adherence of study participants. This presentation will be of interest to clinical research professionals who conduct clinical trials with low income, urban young adults living with HIV/AIDS as well as for those interested in predicting and supporting medication adherence among study participants in general.
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