Title

Low concentrations of nitric oxide exert a hormetic effect on Mycobacterium tuberculosis in vitro

Document Type

Journal Article

Publication Date

9-1-2005

Journal

Journal of Clinical Microbiology

Abstract

Susceptibilities of 12 clinical Mycobacterium tuberculosis isolates to acidified sodium nitrite (ASN) were compared. The results demonstrate that 8 of the 12 isolates exhibited enhanced survival levels in 1.5 mM ASN compared to levels in medium alone, suggesting that low concentrations of reactive nitrogen intermediates have a hormetic effect on M. tuberculosis in vitro. Copyright © 2005, American Society for Microbiology. All Rights Reserved.

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