Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury

Authors

Ahdeah Pajoohesh-Ganji, George Washington University
Mark P. Burns
Sonali Pal-Ghosh, George Washington University
Gauri Tadvalkar, George Washington University
Nicole G. Hokenbury, George Washington University
Mary Ann Stepp, George Washington UniversityFollow

Document Type

Journal Article

Publication Date

4-29-2014

Journal

Brain Research

Volume

Volume 1560

Inclusive Pages

73-82

DOI

10.1016/j.brainres.2014.02.049

Keywords

Amyloid Precursor Protein Secretases--antagonists & inhibitors; Amyloid Precursor Protein Secretases--genetics; Amyloid Precursor Protein Secretases--metabolism; Amyloid beta-Protein Precursor--metabolism; Animals; Aspartic Acid Endopeptidases--genetics; Aspartic Acid Endopeptidases--metabolism; Blotting, Western; Enzyme Inhibitors--pharmacology; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Mice, Inbred C57BL; Mice, Knockout; Microglia--physiology; Motor Activity--drug effects; Motor Activity--physiology; Nerve Fibers, Myelinated--drug effects; Nerve Fibers, Myelinated--metabolism; Nerve Fibers, Myelinated--pathology; Presenilin-1--antagonists & inhibitors; Presenilin-1--metabolism; Recovery of Function--drug effects; Recovery of Function--physiology; Spinal Cord--drug effects; Spinal Cord--metabolism; Spinal Cord--pathology; Spinal Cord Injuries--drug therapy; Spinal Cord Injuries--metabolism; Spinal Cord Injuries--pathology; Time Factors

APA Citation

Pajoohesh-Ganji, A., Burns, M.P, Pal-Ghosh, S., Tadvalkar, G., Hokenbury, N.G., Stepp, M.A., Faden, A.I., Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury, Brain Research, Volume 1560, 29 April 2014, Pages 73-82

Peer Reviewed

1