Title

p38delta mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis

Document Type

Journal Article

Publication Date

1-22-2010

Journal

Cell cycle (Georgetown, Tex.)

Volume

9

Issue

3

DOI

10.4161/cc.9.3.10541

Abstract

The p38delta mitogen-activated protein kinase (MAPK) is abundantly expressed in a wide array of tissues where it is likely to have specific functions. This review aims to highlight recent new insights into the biological roles of this relatively less studied p38 isoform. We focus on function of p38delta in regulating of epidermal keratinocyte differentiation, apoptosis and skin tumor development.

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