Biomarkers of radioresistance in head and neck cancer: a new beginning

Document Type

Journal Article

Publication Date

2-18-2025

Journal

Clinical cancer research : an official journal of the American Association for Cancer Research

DOI

10.1158/1078-0432.CCR-24-4223

Abstract

The development of biomarkers of radioresistance in head and neck cancer may help personalize treatment. This commentary puts in context the findings of a secondary analysis of NRG/RTOG 9512, a trial of fractionation in T2N0 glottic cancer, which observed that NFE2L2/KEAP1/CUL3 mutations are correlated with local recurrence and disease-free survival.

Department

Radiology

Share

COinS