The Care of Adolescents and Young Adults with Turner syndrome: A Pediatric and Adolescent Gynecology Perspective

Authors

Tazim Dowlut-McElroy, Pediatric and Adolescent Gynecology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD; Department of Surgery, Children's National Hospital, Washington DC. Electronic address: tazim.dowlut-mcelroy@nih.gov.
Roopa Kanakatti Shankar, Pediatric and Adolescent Gynecology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD; Division of Endocrinology, Children's National Hospital, Washington DC; George Washington University School of Medicine, Washington DC.

Document Type

Journal Article

Publication Date

3-7-2022

Journal

Journal of pediatric and adolescent gynecology

DOI

10.1016/j.jpag.2022.02.002

Keywords

DSD; Turner syndrome; fertility; hormone replacement therapy; pregnancy complications; preservation; pubertal induction,POI

Abstract

Turner syndrome (TS) is caused by the absence of a part or whole X-chromosome in a phenotypic female and has an estimated prevalence of 25-50/100,000 liveborn females. The primary gynecologic manifestation of TS is Primary Ovarian Insufficiency (POI) and the resulting hypoestrogenism and infertility are experienced by most individuals with TS. In this review, we summarize the recommendations for the care of adolescents and young adults (AYA) with TS, with a focus on primary ovarian insufficiency in TS, hormone replacement therapy, fertility preservation and pregnancy in TS. Powered.

APA Citation

Dowlut-McElroy, Tazim and Shankar, Roopa Kanakatti, "The Care of Adolescents and Young Adults with Turner syndrome: A Pediatric and Adolescent Gynecology Perspective" (2022). GW Authored Works. Paper 623.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/623

Department

Pediatrics