Title

The Care of Adolescents and Young Adults with Turner syndrome: A Pediatric and Adolescent Gynecology Perspective

Document Type

Journal Article

Publication Date

3-7-2022

Journal

Journal of pediatric and adolescent gynecology

DOI

10.1016/j.jpag.2022.02.002

Keywords

DSD; Turner syndrome; fertility; hormone replacement therapy; pregnancy complications; preservation; pubertal induction,POI

Abstract

Turner syndrome (TS) is caused by the absence of a part or whole X-chromosome in a phenotypic female and has an estimated prevalence of 25-50/100,000 liveborn females. The primary gynecologic manifestation of TS is Primary Ovarian Insufficiency (POI) and the resulting hypoestrogenism and infertility are experienced by most individuals with TS. In this review, we summarize the recommendations for the care of adolescents and young adults (AYA) with TS, with a focus on primary ovarian insufficiency in TS, hormone replacement therapy, fertility preservation and pregnancy in TS. Powered.

Department

Pediatrics

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