VINDICATE-P: A Mnemonic for the Many Comorbidities of Atopic Dermatitis

Document Type

Journal Article

Publication Date

10-1-2024

Journal

Dermatologic clinics

Volume

42

Issue

4

DOI

10.1016/j.det.2024.04.006

Keywords

Allergic rhinoconjunctivitis; Asthma; Atopic dermatitis; Eosinophilic esophagitis; Food allergies

Abstract

Patients with atopic dermatitis (AD) are at increased risk of atopic and non-atopic comorbidities. In fact, the Hanifin and Rajka criteria include allergic and infectious comorbidities as a minor criterion. Despite the well-recognized list of comorbidities, the past 15 years greatly expanded the list of recognized comorbidities of AD. This narrative review focuses on comorbidities of AD using a mnemonic, VINDICATE-P: vascular/cardiovascular, infectious, neoplastic and neurologic, degenerative, iatrogenic, congenital, atopic and autoimmune, traumatic, endocrine/metabolic, and psychiatric. The comorbidities of AD vary by age. More research is needed into the mechanisms of comorbidities and optimal screening strategies in AD patients.

Department

Dermatology

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