Bilateral Exudative Retinal Detachments and Panuveitis in a Patient with Multiple Myeloma
Ocular immunology and inflammation
Exudative retinal detachments; hyperviscosity syndrome; multiple myeloma; panuveitis; retinopathy
PURPOSE: To report a case of bilateral exudative retinal detachments and panuveitis in a patient with multiple myeloma (MM). CASE REPORT: A 54-year-old patient with non-proliferative diabetic retinopathy was referred with blurred vision and scotomas in both eyes (OU). Three months prior to the onset of ocular symptoms, he was diagnosed with systemic MM and was receiving chemotherapy. Clinical examination revealed best-corrected visual acuities of 20/80 OU, rare anterior chamber cell, 2+ vitreous cell, diffuse intraretinal hemorrhages, and exudative retinal detachments (RD). Optical coherence tomography of the macula showed central subretinal fluid with cystic intraretinal fluid OU. The findings were consistent with panuveitis and exudative RD in the setting of MM. He reported symptomatic improvement after plasmapheresis and oral prednisone initiation. CONCLUSION: Extensive, bilateral exudative RD and panuveitis are rare but potentially sight-threatening findings in patients with MM.
Nguyen, Nam V.; Konstantinou, Eleni K.; Sherif, Noha; Soifer, Matias; Patronas, Marena; Allen, Joshua; Bellur, Sunil S.; and Kodati, Shilpa, "Bilateral Exudative Retinal Detachments and Panuveitis in a Patient with Multiple Myeloma" (2023). GW Authored Works. Paper 2744.