Treatment of chronic relapsing urinary tract infection with antibiotics selected by AtbFinder
Urology case reports
Antibiotics; AtbFinder; Drug resistant; Susceptibility testing; Urinary tract infection
We report the case of a 46-year-old patient who, after renal cancer surgery, developed a recurrent urinary tract infection that lasted for more than 2 years. Despite repeated antibiotic courses, including broad-spectrum drugs chosen using conventional antibiotic susceptibility testing, multiple reinfections followed. The patient was successfully treated once antibiotics were selected with AtbFinder. Unlike routine antimicrobial susceptibility methods, which select antibiotics effective only against a "lead bacterial pathogen," AtbFinder identifies antibiotics that target the mixture of bacteria at the infection site. This case demonstrates the ability of AtbFinder to successfully select antibiotics for the treatment of relapsing urinary tract infections.
Tetz, George V.; Kardava, Kristina M.; Vecherkovskaya, Maria F.; Tsifansky, Michael D.; and Tetz, Victor V., "Treatment of chronic relapsing urinary tract infection with antibiotics selected by AtbFinder" (2023). GW Authored Works. Paper 2321.