Population Representation in HIV Cure Research: A Review of Diversity Within HIV Cure Studies Based in the United States

Authors

Carly Roberts, Department of Epidemiology, Milken Institute School of Public Health at the George Washington University, District of Columbia, USA.
Emma Creamer, Community Education Group, Inc., District of Columbia, USA.
Cheriko A. Boone, Department of Psychological and Brain Sciences at the George Washington University and currently with Treatment Action Group, District of Columbia, USA.
A Toni Young, Community Education Group, Inc., District of Columbia, USA.
Manya Magnus, Department of Epidemiology, Milken Institute School of Public Health at the George Washington University, District of Columbia, USA.

Document Type

Journal Article

Publication Date

2-21-2022

Journal

AIDS research and human retroviruses

DOI

10.1089/AID.2021.0127

Keywords

HIV cure research; diversity; generalizability; representativeness

Abstract

HIV is experienced across diverse populations, with gender and racial/ethnic minority populations bearing a significant proportion of disease. With National Institutes of Health (NIH) placing a priority on the enrollment of women and racial/ethnic minorities into studies, it is important to understand the diversity of participants in research. We sought to characterize how HIV cure research studies report data on diversity. A sampling frame of publications with funding provided by the Martin Delaney Collaboratories for HIV Research in 2019 was reviewed for reporting of demographic data. Of 55 publications that included research on humans/human specimens, only 51% provided any demographic description. There often is insufficient consideration of diversity of populations in HIV cure research. Ameliorating gaps in this regard will require recruitment of diverse populations/specimens and specifications to report demographic data in articles. This will ensure inclusion of diverse participants in HIV cure research from earliest laboratory to eventual phase III studies.

APA Citation

Roberts, Carly; Creamer, Emma; Boone, Cheriko A.; Young, A Toni; and Magnus, Manya, "Population Representation in HIV Cure Research: A Review of Diversity Within HIV Cure Studies Based in the United States" (2022). GW Authored Works. Paper 127.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/127

Department

Epidemiology