Population Representation in HIV Cure Research: A Review of Diversity Within HIV Cure Studies Based in the United States
AIDS research and human retroviruses
HIV cure research; diversity; generalizability; representativeness
HIV is experienced across diverse populations, with gender and racial/ethnic minority populations bearing a significant proportion of disease. With National Institutes of Health (NIH) placing a priority on the enrollment of women and racial/ethnic minorities into studies, it is important to understand the diversity of participants in research. We sought to characterize how HIV cure research studies report data on diversity. A sampling frame of publications with funding provided by the Martin Delaney Collaboratories for HIV Research in 2019 was reviewed for reporting of demographic data. Of 55 publications that included research on humans/human specimens, only 51% provided any demographic description. There often is insufficient consideration of diversity of populations in HIV cure research. Ameliorating gaps in this regard will require recruitment of diverse populations/specimens and specifications to report demographic data in articles. This will ensure inclusion of diverse participants in HIV cure research from earliest laboratory to eventual phase III studies.
Roberts, Carly; Creamer, Emma; Boone, Cheriko A.; Young, A Toni; and Magnus, Manya, "Population Representation in HIV Cure Research: A Review of Diversity Within HIV Cure Studies Based in the United States" (2022). GW Authored Works. Paper 127.