Post-diagnosis body mass index and mortality among women diagnosed with endometrial cancer: Results from the Women's Health Initiative.

Authors

Hannah Arem, George Washington University
Ruth M Pfeiffer
Steven C Moore
Melinda L Irwin
Michael J LaMonte
Gloria E Sarto
Rami Nassir
Juhua Luo
Rowan T Chlebowski
Louise A Brinton
Charles E Matthews

Document Type

Journal Article

Publication Date

1-1-2017

Journal

PLoS One

Volume

12

Issue

2

DOI

10.1371/journal.pone.0171250

Abstract

Higher body mass index (BMI) measured before endometrial cancer diagnosis has been associated with greater risk of developing endometrial cancer and higher mortality, but the association between BMI measured after diagnosis and mortality risk is unclear. We identified 467 women (91 deaths) in the Women's Health Initiative (WHI) with information on BMI measured after diagnosis and used Cox proportional hazards regression to generate hazard ratios (HR) and 95% confidence intervals (CI) for all-cause mortality. Comparing BMI 35+ with/m2, we observed no association with all-cause mortality (HR = 1.02, 95% CI 0.55-1.91). Our study does not support the hypothesis that higher BMI after endometrial cancer diagnosis is associated with poorer survival.

Comments

Reproduced with permission of PLoS ONE.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

APA Citation

Arem, H., Pfeiffer, R., Moore, S., Irwin, M., LaMonte, M., Sarto, G., Nassir, R., Luo, J., Chlebowski, R., Brinton, L., & Matthews, C. (2017). Post-diagnosis body mass index and mortality among women diagnosed with endometrial cancer: Results from the Women's Health Initiative.. PLoS One, 12 (2). http://dx.doi.org/10.1371/journal.pone.0171250

Peer Reviewed

1

Open Access

1