Population pharmacokinetic modeling and dosing simulations of nitrogen-scavenging compounds: Disposition of glycerol phenylbutyrate and sodium phenylbutyrate in adult and pediatric patients with urea cycle disorders.

Authors

John P.R. Monteleone, Pharsight Corporation
Masoud Mokhtarani, Hyperion Therapeutics, San Francisco, CA
George A. Diaz, Mount Sinai School of Medicine
William Rhead, Medical College of Wisconsin
Uta Lichter-Konecki, George Washington University
Susan A. Berry, University of Minnesota
Cindy LeMons, National Urea Cycle Disorders Foundation, Pasadena, CA
Klara Dickinson, Hyper Therapeutics, San Francisco, CA
Dion F. Coakley, Hyper Therapeutics, San Francisco, CA
Bruce F. Scharschmidt, Hyper Therapeutics, San Francisco, CA
Brendan Lee, Baylor College of MedicineFollow

Document Type

Journal Article

Publication Date

7-2013

Journal

Journal of Clinical Pharmacology

Volume

Volume 53, Issue 7

Inclusive Pages

699-710

APA Citation

Monteleone, J. P. R., Mokhtarani, M., Diaz, G. A., Rhead, W., Lichter-Konecki, U., Berry, S. A., . . . Scharschmidt, B. F. (2013). Population pharmacokinetic modeling and dosing simulations of nitrogen-scavenging compounds: Disposition of glycerol phenylbutyrate and sodium phenylbutyrate in adult and pediatric patients with urea cycle disorders. Journal of Clinical Pharmacology, 53(7), 699-710.

Peer Reviewed

1