Leukemia Research Reports
The V600 BRAF mutation has been described as a key mutation in the pathogenesis of classical hairy cell leukemia (c-HCL) cases without expression of a mutant immunoglobulin heavy chain (IgHV). Here we present a rare case of c-HCL with neither V600 BRAF mutation nor the aforementioned IgHV variant successfully treated with cladribine and review the current literature on its use in women of childbearing age/pregnancy.
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Hossain, A., Rafei, H., Jariwala, A., & El-Shami, K. (2017). A rare breed: Wild-type braf and ighv expression in a 29 year old lady with classical hairy cell leukemia. Leukemia Research Reports, 7 (). http://dx.doi.org/10.1016/j.lrr.2017.01.001