Document Type
Journal Article
Publication Date
2015
Journal
Future Science OA
Volume
1
Issue
1
DOI
10.4155/fso.15.54
Abstract
Harnessing the impressive therapeutic potential of nitric oxide (NO) remains an ongoing challenge. This paper describes several of the current strategies both with respect to the underlying chemistry and physics and to the applications where they have shown promise. Included in this overview are molecular systems such as NONOates that release NO through chemical reactions and delivery vehicles such as nanoparticles that can generate, store, transport and deliver NO and related bioactive forms of NO such as nitrosothiols. Although there has been much positive movement, it is clear that we are only at the early stages of knowing how to precisely produce, transport and deliver to targeted sites therapeutic levels of NO and related molecules.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
APA Citation
Liang, H., Nacharaju, P., Friedman, A. J., & Friedman, J. (2015). Nitric oxide generating/releasing materials. Future Science OA, 1 (1). http://dx.doi.org/10.4155/fso.15.54
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of Future Science Ltd. Future Science OA