Title

Diagnosing Urogenital Schistosomiasis: Dealing with Diminishing Returns

Document Type

Journal Article

Publication Date

5-1-2017

Journal

Trends in Parasitology

Volume

33

Issue

5

DOI

10.1016/j.pt.2016.12.009

Keywords

diagnosis; female genital schistosomiasis (FGS); neglected tropical diseases (NTDs); Schistosoma haematobium; urogenital schistosomiasis

Abstract

© 2016 Elsevier Ltd Urogenital schistosomiasis, caused by Schistosoma haematobium, is the most prevalent form of schistosomiasis affecting humans, and can result in severe bladder, kidney, ureteral, and genital pathologies. Chronic infection with S. haematobium has been linked with bladder cancer and increased risk for HIV infection. As mass drug administration with praziquantel increases in an attempt to transition from control to elimination of schistosomiasis, the need for updated, more sensitive diagnostic tools becomes more apparent, especially for use in areas of low infection intensity and for individuals with light infections. Here, we review established and investigational diagnostic tests utilized for urogenital schistosomiasis, highlighting new insights and recent advances.

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