Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.
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Gu, S., Nguyen, B., Rao, S., Li, S., Shetty, K., Rashid, A., Shukla, V., Deng, C., Mishra, L., & Mishra, B. (2017). Alcohol, Stem Cells and Cancer.. Genes Cancer, 8 (9-10). http://dx.doi.org/10.18632/genesandcancer.156