Outcome in recipients of dual kidney transplants: An analysis of the dual registry patients
Background. A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transplant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipients of kidneys from donors ≥54 years of age who received a single kidney transplant reported to the United Network for Organ Sharing Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry. Methods. A retrospective analysis was performed, comparing four donor and nine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999. Results. Dual versus single transplants from donors ≥54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despite having kidneys from significantly older donors with poorer HLA matching. Conclusions. Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors ≥54 years of age.
Lu, A., Carter, J., Weinstein, R., Stratta, R., Taylor, R., Bowers, V., Ratner, L., Chavin, K., Johnson, L., Kuo, P., Cole, E., Dafoe, D., & Alfrey, E. (2000). Outcome in recipients of dual kidney transplants: An analysis of the dual registry patients. Transplantation, 69 (2). http://dx.doi.org/10.1097/00007890-200001270-00014