Title

PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.

Document Type

Journal Article

Publication Date

8-22-2019

Journal

Nature Communications

Volume

10

Issue

1

DOI

10.1038/s41467-019-11732-6

Keywords

Animals; Antineoplastic Agents; Brain Stem Neoplasms; Cell Line, Tumor; Child; Cytokines; DNA Methylation; Diffuse Intrinsic Pontine Glioma; Epigenetic Repression; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Nicotinamide Phosphoribosyltransferase; Pons; Primary Cell Culture; Protein Phosphatase 2C; Synthetic Lethal Mutations; Xenograft Model Antitumor Assays

Peer Reviewed

1

Open Access

1

Find in your library

Share

COinS