Title

Treatment of bone lesions with cryoprobes

Document Type

Journal Article

Publication Date

6-1-2007

Journal

Techniques in Orthopaedics

Volume

22

Issue

2

DOI

10.1097/BTO.0b013e3181237d2a

Keywords

Bone tumor; Cryoprobe; Cryosurgery; Giant cell tumor of bone; Orthopedic oncology; Orthopedic surgery

Abstract

Cryosurgery, an established and proven technique for the treatment of aggressive bone tumors, has never been used to its potential because of concerns regarding the difficulty and morbidity of applying liquid nitrogen directly to open wounds. A new generation of closed-circuit cryoprobes featuring advanced nozzle designs and control mechanisms appears to solve many of the issues that have formed a barrier to widespread adoption of cryosurgery in orthopaedics. Experience with cryoprobes based on animal models and human studies offers insight into some of the practical techniques needed to effectively treat irregularly shaped cavities in bone. Results suggest that these probes offer the clinical advantages of cryosurgery without many of the problems associated with direct application of liquid nitrogen. © 2007 Lippincott Williams & Wilkins, Inc.

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