Invasive aspergillosis in patients with hiv infection: Report of two patients and a review of the literature
Journal of Acquired Immune Deficiency Syndromes
Summary: Two cases of invasive aspergillosis in AIDS patients are reported and previously reported AIDS-related cases are reviewed. Only one-half of all cases were diagnosed antemortem. Outcome is poor despite antifungal and surgical therapy. Normal phagocytic function is important in host defense against Aspergillus species. HIV-infected patients may have impaired phagocytic function as a result of antiretroviral therapy or treatment of opportunistic infection, or due to HIV infection itself. As the lifespans of HIV-infected patients are extended by antiretroviral therapy, an increasing awareness of Aspergillus infection as an opportunistic pathogen will be necessary. © 1991 Raven Press, New York.
Decker, C., & Parenti, D. (1991). Invasive aspergillosis in patients with hiv infection: Report of two patients and a review of the literature. Journal of Acquired Immune Deficiency Syndromes, 4 (6). Retrieved from https://hsrc.himmelfarb.gwu.edu/smhs_medicine_facpubs/5067