Could erectile dysfunction in type 2 diabetes change the presumption of normative total blood serumtes tos terone ?

Document Type

Journal Article

Publication Date



Medical News of North Caucasus








Erectile dysfunction; Testosterone; Type 2 diabetes mellitus


© Group of authors, 2016. According to research data, the ED is detected in 50-75 % of men with T2DM. During the last decade, the problem of ED in the presence of late onset hypogonadism has been actively studied. There is convincing proof that total serum testosterone (T) deficit influences the development and severity of ED, including in T2DM. The principal aim of the current study was to evaluate ED in males with T2DM at low and middle- To-high normative levels of T. We have performed a prospective randomized simple comparative study of 86 male patients with T2DM and T level higher than 12.0 nmol/l. The patients were divided into two groups, with low normative level of T and with middle - To high normative T levels. Standard methods of objective evaluation did not permit discrimination in the T2DM compensation. At the same time the diseases based on vascular pathology, dyslipidemia and vascular endothelial dysfunctions were more frequently found in patients with middle- To-high normal T levels. In the two groups of patients the severity of androgen deficiency symptoms was found out to be unequal. The IIEF-5 questionnaire showed significant difference in frequency and severity of ED and significant relation to T levels. Males with T2DM and normotestosteronemia at 12-15 mmol/l are at higher risks of dyslipidemia, endothelium disorders and progress of T2DM as compared to males with blood T of>15 mmol/l.