Title

Retransplantation for donor-derived neuroendocrine tumor

Document Type

Journal Article

Publication Date

1-1-2011

Journal

Liver Transplantation

Volume

17

Issue

1

DOI

10.1002/lt.22196

Abstract

Although tumor transmission through liver transplantation (LT) is a rare occurrence, the consequences can be devastating, even when a very aggressive management approach is adopted. We report the case of a donor-derived small cell neuroendocrine tumor (NET) in a patient who underwent LT for cholangiocarcinoma. Despite locoregional therapy, chemotherapy and ultimately retransplantation, the patient died from metastases. The high grade nature of the NET was the most important determinant of prognosis in this case. Our experience suggests that retransplantation for donor-derived NET should only be considered when tumor biology is favorable. Copyright © 2011 American Association for the Study of Liver Diseases.

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