Title

Esophageal Infections in AIDS

Document Type

Journal Article

Publication Date

5-1-1998

Journal

Infections in Medicine

Volume

15

Issue

5

Keywords

Acquired immune deficiency syndrome (AIDS); Candida; Cytomegalovirus (CMV); Esophagitis; Herpes simplex virus (HSV); Human immunodeficiency virus (HIV); Mycobacterium tuberculosis

Abstract

More than half of patients with AIDS will develop esophageal disease. The most common pathogenic organisms causing esophageal symptoms in HIV- infected patients include Candida, herpes simplex virus, and cytomegalovirus, but bacterial infections with Mycobacterium tuberculosis and parasitic infections with Leishmania protozoa have also been reported. HIV itself and the medications used to treat certain opportunistic infections of AIDS have also been implicated as causes of painful esophageal ulcerations. It is important for the clinician to be aware of the myriad clinical manifestations of esophageal disease; of the diagnostic tools available to pinpoint its cause, including radiography, brushings, histology, culture, and endoscopy; and of current regimens for treatment of esophagitis in patients with HIV disease.

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