Journal of Anaesthesiology Clinical Pharmacology
Volume 30, Issue 1
Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review summarizes the different studies documenting the incidence, severity and available recommendations related to this adverse effect.
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Abdallah, C. (2014). Considerations in perioperative assessment of valproic acid coagulopathy. Journal of Anaesthesiology Clinical Pharmacology, Volume 30, Issue 1 (). http://dx.doi.org/10.4103/0970-9185.125685