Pharmacoeconomic Analysis and Considerations for the Management of Kawasaki Disease in the Arab Countries-A Multinational, Multi-Institutional Project of the Kawasaki Disease Arab Initiative (Kawarabi) (A Project Methodology Paper)

Djouher Nait-Ladjemil, CHU Sainte-Justine, University of Montreal, Montreal, Canada.
Ashraf S. Harahsheh, George Washington University School of Medicine and Health Sciences, Washington, USA.
Nadine Choueiter, Mount Sinai Kravis Children's Hospital, Icahn School of Medicine, New York, USA.
Hala M. Agha, Division of Pediatric Cardiology, Cairo University, Egypt.
Hanifa Alrabte, Department of Pediatric Cardiology, Tripoli Children Hospital, Tripoli, Libya.
Sima Y. Al-Saoud, Department of Pediatrics, Al-Quds University Faculty of Medicine, Makassed Hospital, Jerusalem, Palestine.
Hesham Al-Saloos, Division of Cardiology, Sidra Medicine, Clinical Pediatrics, Weill Cornell Medicine, Qatar.
Khalfan Al Senaidi, Division of Pediatric Cardiology, Sultan Qaboos University Hospital, Muscat, Oman.
Raed Alzyoud, Pediatric Immunology, Allergy, and Rheumatology Division, Queen Rania Children's Hospital, Amman, Jordan.
Zainab Al Awadhi, Al Jalila Children's Speciality Hospital, Dubai, United Arab Emirates.
Reda Belbouab, Pediatric Department University Hospital, Mustapha Bacha Algiers, Algiers University Faculty of Medicine, Algiers, Algeria.
Asma Bouaziz, Headmaster of Children and Neonatal Department, Hôpital Régional Ben Arous, Tunisia.
Mona El Ganzoury, Division of Pediatric Cardiology, Department of Pediatrics, Ain Shams UniversityFaculty of Medicine, Cairo, Egypt.
Zohra Fitouri, Division of Rheumatology, Emergency Department of Béchir Hamza Pediatric Hospital of Tunis, Tunisia.
Alyaa Kotby, Pediatric Cardiology Division, Department of Pediatrics, Ain Shams University Faculty of Medicine, Cairo, Egypt.
Mohamed S. Ladj, Department of Pediatrics, Djillali Belkhenchir University Hospital, Algiers University Faculty of Medicine, Algiers, Algeria.
Mohammed Mokhtar Bekkar, Department of Pediatrics, Pediatric Cardiology Unit, Oran University Faculty of Medicine, CHU Oran, Algeria.
Najat Rugige, Department of Pediatric Cardiology, Benghazi Children Hospital, Benghazi University, Benghazi, Libya.
Aso Faeq Salih, Department of Pediatric Cardiology, Children's Heart Hospital-Sulaimani College of Medicine-Sulaimani University, Al-Sulaimaniyah, Iraq.
Mohamed Sulaiman, KidsHeart Medical Center, Abu Dhabi, United Arab Emirates.
Nagib Dahdah, CHU Sainte-Justine, Montreal, Canada.

Document Type

Journal Article

Publication Date

3-3-2025

Journal

Turkish archives of pediatrics

Volume

60

Issue

2

DOI

10.5152/TurkArchPediatr.2025.24248

Abstract

Objective: Kawasaki disease (KD) poses a significant risk of childhood-acquired coronary artery disease. There is a notable scarcity of comprehensive KD data from low- and middleincome Arab countries, giving rise to concerns about the underestimation of KD outcomes. To bridge these gaps, the Kawasaki disease Arab initiative (Kawarabi) was established to reinforce education, advocacy, and enhance patients' health outcomes. This project's primary objective is to assess the economic burden and disease-related costs affecting KD management in the Arab world, contextualized within the economic status and healthcare infrastructure of each respective country. Materials and Methods: The project employs a thorough pharmacoeconomic (PE) analysis, emphasizing societal implications, including patient expenses, hospital costs, and impacts on both the public healthcare system and private insurers. A multifaceted cost analysis methodology considers the impact of delays in acute management and potential cardiac complications, addressing hypothetical scenarios to quantify costs associated with different outcomes. Results: Unique perspectives of PEs in Arab countries and its crucial role in informing healthcare decision-making are analyzed. The project delves into the transformative role of PEs in healthcare systems. The project's exploration of KD in the Arab world anticipates significant contributions to the global understanding of KD challenges. The commitment to overcoming obstacles and addressing health disparities through the transformative lens of PEs reflects a dedication to making a positive impact on KD-related public health. Conclusion: The project is emphasized by offering actionable recommendations for KD management in low- to moderate-income Arab countries, in particular, and the Middle East, in general.

Department

Pediatrics

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