A Rare Case of Concurrent Primary Biliary Cholangitis and Sarcoidosis

Authors

Robert S. Gordon, Internal Medicine, George Washington University School of Medicine and Health Sciences, Washington, USA.
Mrudula Bandaru, Internal Medicine, George Washington University School of Medicine and Health Sciences, Washington, USA.
Laxmikausthubha Yaratha, Internal Medicine, George Washington University School of Medicine and Health Sciences, Washington, USA.
Marie L. Borum, Gastroenterology and Liver Diseases, George Washington University School of Medicine and Health Sciences, Washington, USA.
Mamoun Younes, Pathology, George Washington University School of Medicine and Health Sciences, Washington, USA.

Document Type

Journal Article

Publication Date

3-1-2025

Journal

Cureus

Volume

17

Issue

3

DOI

10.7759/cureus.80228

Keywords

case report; granulomatous liver disease; hepatic sarcoidosis; peripheral eosinophilia; primary biliary cholangitis (pbc)

Abstract

Primary biliary cholangitis and sarcoidosis are the two most common causes of granulomatous liver disease in the US; however, their expected clinical course and management are starkly different. This case involves a patient with granulomas noted on liver biopsy, presumed secondary to known sarcoidosis, later found to have concurrent primary biliary cholangitis. Prompt diagnosis of primary biliary cholangitis is crucial as its natural course of progressive liver fibrosis can be significantly improved with treatment.

APA Citation

Gordon, Robert S.; Bandaru, Mrudula; Yaratha, Laxmikausthubha; Borum, Marie L.; and Younes, Mamoun, "A Rare Case of Concurrent Primary Biliary Cholangitis and Sarcoidosis" (2025). GW Authored Works. Paper 6839.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/6839

Department

Pathology