Acral Lentiginous Melanoma. Part II. Staging, Surgical Management, The Role of Systemic Therapy, Shortcomings and Future Directions

Authors

Daniella Jaguan, Georgetown University School of Medicine, Washington, DC.
Sach Thakker, Georgetown University School of Medicine, Washington, DC.
Micah Belzberg, Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD; Department of Dermatology, Cleveland Clinic, Cleveland, OH.
Nina Gulati, Tufts University School of Medicine, Boston, MA.
Janeth R. Campbell, Georgetown University School of Medicine, Washington, DC.
Brittney K. DeClerck, Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA; Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Vishal A. Patel, Department of Dermatology, George Washington University, Washington, DC.
Gino K. In, Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA; Division of Oncology, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA. Electronic address: Gino.In@med.usc.edu.

Document Type

Journal Article

Publication Date

1-7-2025

Journal

Journal of the American Academy of Dermatology

DOI

10.1016/j.jaad.2024.11.076

Keywords

acral lentiginous melanoma; chemotherapy; cutaneous oncology; dermatologic surgery; immunotherapy; melanoma; targeted therapy

Abstract

This comprehensive review navigates the clinical management and challenges of acral lentiginous melanoma (ALM), including staging, surgical interventions, and systemic therapies. Multimodality treatment and clinical trials are recommended for advanced cases.

APA Citation

Jaguan, Daniella; Thakker, Sach; Belzberg, Micah; Gulati, Nina; Campbell, Janeth R.; DeClerck, Brittney K.; Patel, Vishal A.; and In, Gino K., "Acral Lentiginous Melanoma. Part II. Staging, Surgical Management, The Role of Systemic Therapy, Shortcomings and Future Directions" (2025). GW Authored Works. Paper 6400.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/6400

Department

Dermatology