The bidirectional interplay of obstructive sleep apnea and viral respiratory infections in children: A novel opportunity for primary prevention
Document Type
Journal Article
Publication Date
10-4-2024
Journal
Pediatric pulmonology
DOI
10.1002/ppul.27314
Keywords
OSA; adenoids; children; tonsils; viral respiratory infections
Abstract
Obstructive sleep apnea (OSA) and viral respiratory infections are highly prevalent conditions in children and a major cause of respiratory morbidity in this age group. Severe viral respiratory infections are a known risk factor for pediatric OSA, which is primarily caused by hypertrophy of upper airway lymphoid tissues (adenoids and tonsils). This review examines recent progress in understanding early-life development of lymphoid tissues in the human upper airway, with a particular focus on how respiratory viruses may influence this process and contribute to OSA pathogenesis. It also explores the bidirectional relationship between OSA and severe viral infections, highlighting the need for ongoing monitoring and novel primary prevention strategies to address these interconnected conditions.
APA Citation
Nino, Gustavo; Chorvinsky, Elizabeth; Bhattacharya, Surajit; and Gutierrez, Maria J., "The bidirectional interplay of obstructive sleep apnea and viral respiratory infections in children: A novel opportunity for primary prevention" (2024). GW Authored Works. Paper 5876.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/5876
Department
Pediatrics